Treatment of refractory generalized convulsive status epilepticus with enteral topiramate in resource limited settings
نویسندگان
چکیده
منابع مشابه
Treatment of refractory generalized convulsive status epilepticus with enteral topiramate in resource limited settings
PURPOSE To explore the feasibility, safety and efficacy of enterally administered topiramate (TPM) as an adjunctive treatment for adult patients with refractory generalized convulsive status epilepticus (RGCSE). METHODS This prospective open-label non-randomized clinical trial was performed at Namazee hospital, Shiraz University of Medical Sciences, Shiraz, Iran from January 2013 through Febr...
متن کاملCurrent Treatment for Generalized Convulsive Status Epilepticus in Adults.
Status epilepticus (SE) is defined as a seizure lasting longer than 5 min, or at least two seizures without full recovery of consciousness between them. Early emergent medical management consists of life support and an etiology survey, and subsequent treatment can be classified into 4 stages: (1) early SE, (2) established SE, (3) refractory SE, and (4) super-refractory SE. For early SE, benzodi...
متن کاملEfficacy of topiramate in children with refractory status epilepticus.
PURPOSE Status epilepticus (SE) is a life-threatening medical condition associated with significant morbidity and mortality that requires urgent medical intervention. Although several agents are available to treat SE, they occasionally fail to abort seizure activity. Topiramate (TPM) was anecdotally reported to be effective in adult patients with refractory SE. In this study, we evaluated the e...
متن کاملTopiramate in the Treatment of Generalized Convulsive Status Epilepticus in Adults: A Systematic Review with Individual Patient Data Analysis
BACKGROUND Generalized convulsive status epilepticus (GCSE) is a medical emergency associated with high morbidity and mortality that requires prompt medical intervention. Topiramate (TPM) is an antiepileptic drug effective against a broad spectrum of seizure types, and has been proposed as a possible therapeutic option for super-refractory status epilepticus (SRSE), the most severe form of GCSE...
متن کاملefficacy of continuous high dose midazolam infusion in childhood refractory generalized convulsive status epilepticus
objecive prolonged and uncontrolled refractory status epilepticus (se) is a life-threatening medical emergency in children (1,2,3). there is no consensus on the optimal therapy for refractory status epilepticus (1). the aim of this study was to develop a new method for treating patients with refractory status epilepticus. materials & methods ten children with refractory status epilepticus in mo...
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ژورنال
عنوان ژورنال: Seizure
سال: 2015
ISSN: 1059-1311
DOI: 10.1016/j.seizure.2014.09.009